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Correspondingly, the protective effects of antioxidant supplementation have been observed in experimental models of NAFLD 15,16,17,18

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Cellular levels of both -Glu-Cys and reduced GSH levels were significantly decreased (Supp Fig 3B), consistent with our hypothesis that the PfMRP1 mutant increases efflux of reduced GSH

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In addition, a special mu loop (EAGGPPDFS) between 2 and 2 was found