2006 Sep;114(9):1438-44
With sufficient glutathione present, NAPQI is very quickly metabolized into sulfate and cysteine compounds, which are readily excreted through the kidneys.[ref] However, when it isnt neutralized, NAPQI is highly reactive and can cause oxidative stress and damage to the liver cells, hepatocytes, leading to cell death
This precaution helps prevent any unforeseen interactions and ensures safe use of the injection alongside other treatments
diosgenin, charantin, and hydroxychalcone from the formulations F1 and F2, the relative bioavailabilities for these were calculated and the results are presented in Table 9
As expected, xCT overexpression increased intracellular Cys levels (Fig
Baron also says these reactions resolve on their own if you just lower the concentration a bit (or the frequency, perhaps)