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Tirzepatide (Mounjaro for type 2 diabetes, Zepbound for weight management) is an FDA-approved dual GIP/GLP-1 receptor agonist that reduces appetite and slows gastric emptying

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PIP 3 also interacts with proteins possessing a pleckstrin homology (PH) domain, such as protein kinases, including Akt and Bruton's tyrosine kinase (BTK)

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Several neurocognitive peptides have shown memory and cognition effects in animal models and small human studies, primarily through pathways involving BDNF (brain-derived neurotrophic factor), nerve growth factor, and synaptic plasticity