Largest reductions (18-20%) occurred in the high-dose group after 1 and 2 weeks Combined dose groups significantly reduced the ratio by 14% after 1 and 2 weeks The decreases observed in oxidized:reduced GSH as a result of oral liposomal GSH supplementation are likely indicative of a general systemic reduction in oxidative stress levels. Plasma levels of 8-isoprostane (a marker of oxidative stress) decreased after liposomal glutathione supplementation
"We can just look at these biomarker results and just say 'This person has severe TBI' and 'This person has a mild TBI' without even assessing them in any other way," said University of Montana Assistant Research Professor Tom Rau
Tao X, Zheng J-M, Xu A-M, Chen X-F, Zhang S-H
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To determine whether VPA-induced synaptic changes were driven by pre- or post-synaptic alterations, we also examined VGLUT-1 and PSD-95 individually
Funnel plots were visibly inspected for evidence of publication bias (Supplemental Figs