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In one mouse study, researchers found that the peptide reduced the pain felt by the animals in their paws when placed on a mildly hot plate. The authors explained that this could be because GHK is similar in structure to cimetidine, a histamine H2 receptor antagonist sometimes given to reduce pain in certain digestive conditions.3 10 In rodents, doses as low as 0.5mg/kg were found to be effective in delivering these anti-pain effects.25 In a 70kg human, an equivalent dose would be around 5.6mg, though thats likely higher than necessary: pharmaceutical-grade GHK-Cu normally ranges from 0.5 mg to 2.5mg per injection

Endothelial cell studies report increased proliferation, migration, and tube formation in culture systems that measure angiogenic signaling behavior

References Balenovic D, Udovicic M, Zivanovic-Posilovic G, et al

Oral liquid is second best for gut-specific goals

[DOI] [PubMed] [Google Scholar] 297.Tlak Gajger I., Smodi kerl M.I., otari P., uran J., Sikiri P., Vlaini J

CAS 42464-96-0)