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Studies on their pharmacokinetics and distribution in the human brain

Safe and vegetarian, suitable for long-term daily use

However, if taken on a long-term basis, it may cause side effects, such as constipation and vomiting

Swanson CA, Patterson BH, Levander OA, Veillon C, Taylor PR, Helzlsouer K et al

These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including amlodipine and the angiotensin II receptor blocker (ARB) class to which valsartan principally belongs

The brain is particularly sensitive to oxidative stress because of its high metabolic rate