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Unlike other growth hormone secretagogues, Ipamorelin is distinguished by its ability to elicit GH release without elevating the levels of cortisol or prolactin, which are known to affect energy balance and mood adversely

2002 Jun;4(3):455-64. [PMID: 12215212]

Furthermore, combination metformin and 1.8 Gy radiation treatment significantly increased the percentage of early apoptotic HCT116 cells, when compared to irradiated vehicle control ( Figure 3B )