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Yes, tirzepatide can indirectly cause menstrual irregularities through significant weight loss and metabolic changes that affect reproductive hormone balance

313 YanX.LiuD.-F.ZhangX.-Y.LiuD.XuS.-Y.ChenG.-X.et al (2017)

BMDL: Benchmark dose lower

Water molecules, enzymes, and potential microbial contaminants can begin to cleave the peptide bonds, slowly but surely rendering the compound useless

Endothelial IGF- 1R knockdown impairs skeletal muscle strength without causing significant muscle atrophy Skeletal muscle mass plays a critical role in determining the maximal force output, and its reduction can severely impair muscle strength [52,53,54,55]

Therefore, this could be clearly generalized, and thus, its own effect unmistakably ascribed only to the given peptide (for review, see Seiwerth et al., 2018)