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Premature infants are exposed to a relatively hyperoxic environment when requiring oxygen support

Learn when symptoms peak and proven management strategies from clinical trials

For instance, the synergistic action of BRSV and Histophilus somni downregulated tight junction proteins and stimulated the aberrant secretion of matrix metalloproteinases (notably MMP1 and MMP3), thereby accelerating structural degradation and inflammatory infiltration 101

The chronic activation of the HPA axis due to stress can lead to elevated levels of cortisol, a hormone known to have neurotoxic effects (Mbiydzenyuy and Qulu 2024)

It principally participates in the regulation of blood pressure and vascular tone

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