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Acknowledgments This work was supported by the National Natural Science Foundation of China (grant 81670336) and the Wenzhou Grant for Scientific Talents (RX2016003), Wenzhou Science and Technology Bureau

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Tumor-associated macrophages (TAMs) These are immune components found mostly in tumors and are often manipulated by the tumor to enhance its growth and reduce the effectiveness of immune attacks against it

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doi: 10.1111/j.1469-8137.2011.03889.x 3 BendahmaneA.KanyukaK.BaulcombeD

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