a , b ) Total dopamine content in the striatum of Trkb Penk-KO decreases significantly by 89 months of age (43%) after the initial increase at around three months (DA, 3.5 M vs 89 M, p = 0.007)
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There were no significant differences in early apoptosis and necrosis between untreated and MVs treated groups for both time points compared to day 0
Some newer meta-analyses report a small improvement on the NIHSS stroke scale, while functional independence was not clearly better
This indicates that a further role of the intracellular phase may be to favor the paracellular crossing of host barriers by the bacteria