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Deficient SHBG may contribute to the pathogenesis of inflammation by modulating the biological effects of sex hormones (testosterone and estrogen) on peripheral tissues (liver, muscle, and fat) [120,121]

The pathophysiological process of CVD is multifactorial and can be affected by tea components in several processes: anti-hypertension, lipid-lowering effects, anti-oxidation, anti-inflammation, anti-proliferation, anti-angiogenesis, anti-AS, recovery of endothelial function, anti-thrombosis, myocardial protective effect (Figure 2)

Springer Nature Switzerland, Cham, pp 577582 Lin Q, Li K, Chen Y et al (2023) Oxidative stress in diabetic peripheral neuropathy: pathway and mechanism-based treatment

Bekinschtein P, Kent BA, Oomen CA, Clemenson GD, Gage FH, Saksida LM, et al