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J Thorac Cardiovasc Surg 158(5):1475-1478, 2019

It is a precursor to kynurenine, a metabolite that has immunosuppressive effects

D.Melwani DaswaniM

McGettrick, A

NOR promoted the differentiation and function of Treg cells in intestinal tissue of CIA mice (in an AhR-dependent manner) by activating AhR, and thus played an anti-arthritis role (82)

The second disrupts lipid peroxide repair at or downstream of GPX4 through direct enzyme blockade or by accelerating GPX4 loss and depleting its cofactors