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2.1 Morphological and functional changes of glial cells in PD patients 2.1.1 Oligodendrocytes In the central nervous system, oligodendrocytes are mainly responsible for producing and maintaining the myelin sheath of neurons

This is made possible by 3D-printed IDB trays that hold brackets precisely in place

There are several signaling pathways, such as the phosphoinositide 3-kinases (PI3K)/protein kinase-B (Akt) pathway and the nuclear factor erythroid 2-related factor 2 (Nrf2)/nuclear factor kappa B (NF-B) pathway, which demonstrates a decrease in the inflammatory reaction and mediators upon activation of 7nAChRs [35, 36]

- cerebral or cardiac ischaemia episodes during the past 6 months

Surprisingly, this heightened immune activity actually provides some protection against skin cancer due to increased immune surveillance

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