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Other Risk Factors In addition to the abovementioned risk factors, TBI and gut dysbiosis represent additional risk factor for PD, potentially through overlapping mechanisms involving chronic neuroinflammation and the aggregation of misfolded proteins

Rare nausea, diarrhea and cramping have been reported

Light therapy for non-seasonal depression

Its core function is to promote the formation of new connections between neurons by binding to hepatocyte growth factor (HGF) with high affinity and enhancing the activity of its receptor c-Met

Thus, unneutralized ROS produced in the brain mitochondria of autistic individuals form a positive feedback, a vicious cycle, leading to incrementally growing damage to the mitochondria, which may ultimately result in cell death

However, the poor bioavailability of pirfenidone and the lack of tumor specificity have limited its efficacy