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Gut 3:A309 Vukojevi J, Siroglavi M, Kanik K, Kralj T, Stani D, Kokot A, Kolari D, Drmi D, Sever AZ, Barii I, uran J (2018) Rat inferior caval vein (ICV) ligature and particular new insights with the stable gastric pentadecapeptide BPC 157
Animal studies have failed to establish a lethal dose even at concentrations thousands of times above therapeutic levels
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Half-life ~30 min plasma half-life reported in rat models (subcutaneous administration)
While some people notice no change at all, others may see new or worsening breakouts
Injection site redness (mild, transient) Minor swelling at injection area Occasional headache Mild nausea (typically resolves) Fatigue during initial days Sleep changes (some report disturbance, others improvement) Increased appetite Vivid dreams Temporary digestive changes Sleep effects vary considerably among users
