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van Geldermalsen M, Wang Q, Nagarajah R, Marshall AD, Thoeng A, Gao D, et al
Topical tranexamic acid, arbutin, kojic acid, and azelaic acid can all be helpful when addressing hyperpigmentation, either instead of hydroquinone or in tandem with it
For IBS-C, first-line options include polyethylene glycol, linaclotide, plecanatide, and tenapanor
Pflg ArchEur J Physiol 474(1):2131 Russo I, Frangogiannis NG (2016) Diabetes-associated cardiac fibrosis: cellular effectors, molecular mechanisms and therapeutic opportunities
Recent work has highlighted persistent challenges in metabolomics and ML-based biomarker discovery, including variability in sample preparation, platform-dependent effects, and the risk of overfitting in high-dimensional datasets 76,77
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