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Mechanism of Action at the Cellular Level BPC-157 exerts its effects through multiple interconnected pathways: Angiogenesis Promotion BPC-157 upregulates vascular endothelial growth factor (VEGF) and VEGFR2 expression, stimulating the formation of new capillaries

V.R.J reports consulting fees from Novo Nordisk and receiving honoraria for lectures given for Eli Lilly and educational institutes

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Additionally, functional prediction using PICRUSt2 revealed significantly enhanced microbial pyruvate and butanoate metabolism pathways, supporting the remodeling of microbial metabolic function

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PPARa activation rescues neuronal loss induced by TSCI and promotes motor function recovery PPAR agonists primarily function as co-ligands by binding to PPARs, thereby facilitating nuclear translocation and transcriptional activation