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Graphical Abstract Similar content being viewed by others Introduction Skin cancer (SC), is one of the most devastating cancers of the present decade, and the fifth commonest form of cancer [1,2,3]

Eileen White and have previously been described(Degenhardt et al., 2002)

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In this study, to examine the role of hepatic GSH depletion on protein oxidation and MASLD progression, we have overexpressed Chac1 specifically in liver to induce GSH depletion