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Limitations: Subjective reporting was heavily relied upon in these studies

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MS (Mass Spectrometry): To verify the exact 15-amino acid sequence and molecular weight

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Upon recognition, macrophages undergo proinflammatory polarization and phagocytose of oxidized low density lipoprotein (oxLDL), ultimately leading to proatherogenic cytokine production and the formation of foam cells that contribute to plaque progression 2 (Fig