UMP, much like IMP, serves as the intermediate to pyrimidine synthesis and can undergo sequential phosphorylation to form UTP, which can be converted to cytidine (CTP)
However, the reduction in oxygen metabolism due to a mitochondrial dysfunction may play a role in migraine prevention since an increase in RF concentration might enhance the brain mitochondrial functions [76]
Keeps vitamins C and E active as antioxidants
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Beyond direct antioxidant activity, GSH functions as an obligatory cofactor for a family of enzyme systems that are central to cellular defence: glutathione peroxidases (GPx), which reduce peroxides and lipid hydroperoxides using GSH as the reducing substrate