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That activating versus calming pattern is not absolute, and individual responses vary

3.2.4 Ferroptosis and amyotrophic lateral sclerosis ALS is a lethal NDD characterized by progressive degeneration of upper and lower motor neurons in the cerebral cortex, brainstem, and spinal cord, leading to skeletal muscle atrophy, weakness, weight loss, dysarthria, dysphagia, paralysis, and ultimately death from respiratory failure (Feldman et al., 2022)

TFR1: transferrin receptor 1

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[DOI] [PubMed] [Google Scholar] 58.Manoj K.M., Jaeken L