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doi: 10.1089/nat.2017.0680 106 ShardaNKhandelwalPZhangLCaceres-CortesJMarathePChimalakondaA

A 2023 clinical trial demonstrated this relationship: high-dose nicotinamide riboside supplementation at 3,000 mg daily increased blood NAD+ levels five-fold while maintaining stable glutathione and GSSG levels [12]

Glutathione, a powerful antioxidant, is a difficult ingredient to handle due to its strong odor and stability, making it difficult to prescribe highly concentrated formulas on its own

First, patients getting higher-than-intended doses often due to mislabeling or misunderstanding can experience severe nausea, vomiting, dehydration, and require urgent care

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