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After phosphorylation by JAKs, STATs homo and heterodimerise and form transcription factor complexes that translocate into the nucleus where they induce the expression of IFNstimulated genes (ISGs

Male rats with PTSD-like behaviors showed elevated p -cresol (a neurotoxic metabolite linked to overgrowth of Ruminococcaceae and Lachnospiraceae ) in prefrontal cortex, leading to dopaminergic dysfunction with increased DA, increased dopamine metabolite 3,4-dihydroxyphenylacetic acid (DOPAC), and significantly elevated DA D3 receptor expression compared to controls (Laudani et al., 2023)

It is vital to handle the peptide gently

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Consistent with previous reports, nearly 2/3s of DMP-associated genes in this study were involved in the dysregulation of type I/II IFNs or both