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A key event in this activation is the unwinding of the U4/U6 snRNA duplex, followed by the release of the U4 snRNP and B-specific proteins, and the recruitment of various protein complexes such as the NTC (Nineteen), NTR (Nineteen-related), RES (retention and splicing), and IBC (intron-binding) 12,13,14,15,16
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Atf3 is a stress-responsive transcription factor and Ddit3 is a known apoptosis-promoting transcription factor 40,41
doi:10.1007/s00253-004-1751-y Li W, Li Z, Ye Q (2010) Enzymatic synthesis of glutathione using yeast cells in two-stage reaction