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Functional imaging of legumain in cancer using a new quenched activity-based probe

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Taken together, these results show that the inhibition of SHMT with sertraline in combination with RT reshapes the tumor microenvironment and alleviates the immunosuppressive phenotype, showing an improved NK-associated anti-tumor immune signature and tumor growth delay

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How is PT-141 packaged

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2024 Jan 1;234:173677

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