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With a vitamin B12 deficiency comes the risk of suffering from megaloblastic anemia, including symptoms of fatigue, weakness, pale skin, lack of appetite, infertility, and unexplained weight loss

Mild oxidative agents such as the reactive nitrogen species (RNS) are therefore potentially more relevant from a mechanistic point of view in vivo, as they modify thiols in a more controlled and often reversible manner

And call your doc if anything gets worse

But for researchers who depend on precise concentrations and consistent bioactivity across experiments, the reconstitution step is where errors are most likely to be introduced, and where attention to detail pays the most dividends

Flaxseed for hypertension: implications for blood pressure regulation

10.1097/MPG.0000000000003759 J Pediatr Gastroenterol Nutr