We're talking about effects on tendons, ligaments, muscle, bone, and even the nervous system and gut lining
Additionally, the functionalization of POx with targeting ligands like antibodies or peptides makes these systems more effective in reaching the diseased tissues, thus moving closer to the goal of personalized medicine [25,26,27]
IVW, inverse variance weighted
Glutathione is believed to influence melanin production by inhibiting the enzyme tyrosinase, which plays a role in pigmentation
Hence, GSTs could be useful for product transformation but also for synthetic biology or metabolic engineering approaches, with the aim of generating new chemical entities
This process is part of melanogenesis, where the pigment is made and then transferred to surrounding skin cells