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Szrok-JurgaSCzumajATurynJHebanowskaASwierczynskiJSledzinskiTet al

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B vitamins are best known for supporting a healthy nervous system in patients of all ages

One of the most studied experimental skin sensitizers, 2,4-dinitro-1- chlorobenzene (DNCB), was shown to readily interact with GSH, depleting the cellular levels completely by 4 h when applied at a subtoxic concentration to HaCaT cells

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Collectively, this synergistic approach depletes GSH, generates substantial ROS, and enhances PMBs bactericidal efficacy through membrane disruption ( Figure 6A )