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Erratic timing

One of the few clinical trials involving humans was actually able to corroborate this finding in patients following ST elevation myocardial infarction (STEMI)

When the immune privilege is compromised (e.g., endplate fracture) or the disc is degenerated, disc cells start to express Fas receptor and transiently up-regulate FasL expression

Pfirrmann, C

Important caveat: human efficacy is unproven

The article highlights that Semaglutide monotherapy provides statistically significant and clinically meaningful weight loss, with the majority of patients experiencing a reduction of 5% or more of their body weight