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In: Allen A, Flemstrom G, Garner A, Silen W, Turnberg LA, et al., editors

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These small non-coding RNAs regulate approximately 30% of protein-coding genes involved in cell differentiation, growth, and apoptosis during PCa pathogenesis [49-51]

NAD + is also a precursor to cyclic ADP-ribose (cADPR), a secondary signaling molecule generated by enzymes such as cluster of differentiation 38 (CD38) 7 , and it can be hydrolyzed by sirtuins, which deacetylate histones and regulate gene expression 7

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