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Tissues were infiltrated with paraffin and H&E sections were obtained

Direct cellular damage: Lipase directly targets pancreatic cells, disrupting cell membranes and increasing cellular permeability

Targeting NETs using dual-active DNase1 variants

Although peak plasma ammonium levels are typically in the range of 100500 mol/L in organic acidemia and congenital lactic acidosis, in neonatal onset urea cycle disorders they are generally above 500 mol/L

Deficiency in vitamin B12 is also associated with disproportionate fetal growth (low muscle mass and excess fat mass), increased insulin resistance, intrauterine growth restriction, and lifelong susceptibility to certain chronic diseases