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In some embodiments, an otic composition or formulation disclosed herein comprises less than about 10 ppm of each of C1-C6 alcohols or C1-C6 glycols

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It has been administered by intranasal and intrabronchial routes as well

1 2 3 "B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin"

Acknowledgments/Funding: The authors would like to thank Drs

International sports authorities (WADA / USADA) These compounds are treated as prohibited in sport