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In 2014, the GLS inhibitor CB-839, undergoing clinical trials, was reported to possess potent anti-tumor activity, offering a novel avenue for targeted cancer therapy through modulation of glutamine metabolism [14]

261 Several PMO-based NADs have been approved for treating DMD, including eteplirsen (Exondys 51), 262 golodirsen (Vyondys 53 ), 80 viltolarsen (Viltepso ), 263 and casimersen (Amondys )

Choi MS, Choi D, Choi MH, Ji Z, Li Z, Cho SY, Hong KS, Rim HJ, Hong ST

folic acid is contraindicated

Drug assays measuring eryptosis were carried out in 100 l or 500 l of culture when using 4% or 0.4% hematocrit conditions, respectively