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In a recent study, results indicated significant and sustained clinical neurological improvement

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Compound 3 , ( E )2(3,4dihydroxy5nitrobenzylidene) N phenylhydrazine1carbothioamide, was potent in the order of nM, with an IC 50 value of 0.0437 M, being 734 times more potent than its analog 3,4dihydroxy5nitrobenzaldehyde (DHNB) and 173 times more potent than the drug allopurinol, demonstrating its excellent inhibitory activity (Figure 4)

J., Leighton, B