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434 Patients with PDPN have increased epineurial blood flow and intravascular oxygen saturation, perhaps secondary to arteriovenous shunting due to sympathetic denervation

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Recent therapeutic approaches focus on enhancing insulin signaling pathways or reducing insulin resistance within peripheral nerves to improve neuropathic symptoms (Fig

(2) Mechanism of Action: The drug selectively stimulates -adrenergic receptors in the detrusor smooth muscle, leading to relaxation during the filling phase and increased bladder capacity

10.1007/978-3-642-17214-4_14 82 NakanishiT.ShimazawaM.SugitaniS.KudoT.ImaiS.InokuchiY.et al (2013)

A 10-unit draw (0.1mL) = 50mcg