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In preclinical heart failure models, NNMT enzyme inhibition markedly reduced cardiac 1-MNA (by 77.1%), improved cardiac function, reduced left ventricular hypertrophy and fibrosis, and decreased pro-inflammatory gene expression

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44 Mercury exerts its toxic effects by competing with and displacing iron and copper from the active site of enzymes involved in energy production

[DOI] [PubMed] [Google Scholar] Shirin H