Moreover, the small molecules erastin and sorafenib could block system Xc function, triggering ferroptosis in cancer cells derived from the liver, kidney, and lung (Louandre et al., 2013
Additionally, the cells showed elevated levels of ceramide at the plasma membrane surface
I: physiology and biochemistry
DNA damage promotes mutations of suppressor in tumor such as calcium/calmodulin dependent serine protein kinase (CASK), p53, as well as stimulation of the epidermal growth factor receptor (EFGR) signaling pathway, which are important early events in gastric carcinogenesis (86, 87)
These findings highlight the diverse strategies employed to overcome MDR pathogens, underscoring the importance of combining natural and synthetic antibiotic potentiators in the fight against antimicrobial resistance
Main, P