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Activated ACC catalyzes the synthesis of malonyl-CoA from acetyl-CoA, the rate-limiting step in FA synthesis

It can cause lumps, irritation, and slower absorption

The Importance of Metabolism Besides dose, what your body does with a particular substance, how it gets metabolized and the biologic effect those metabolites exert are all critical factors in determining if that substance is truly friend or foe

Long-term: Muscle loss risk (recommend protein/exercise)

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Malabsorption associated with gluten enteropathy, do oral contraceptives interfere with folate metabolism