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Previous studies have also linked LDHA to OA by regulating AMPK function

Cancer Biol Ther 5:4927, PMID: 16582599 Haouzi D, Lekehal M, Tinel M, Vadrot N, Caussanel L, Lettron P, Moreau A, Feldmann G, Fau D, Pessayre D (2001) Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice

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Over 24 hours at room temperature, NAD + showed tendency to increase by approximately 25% and NADH by 125% from the baseline at collection, while NADP + remained stable and NADPH levels decreased 69% (Supplementary Figure 1a-f)

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1997;51(Suppl 1):S203