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Nutrients (2023) 15:743

With respect to the substantial similarity criteria, the applicant believes that CYTALUX is not substantially similar to other currently available technologies because there are no other optical imaging agents with the same active ingredient, nor the same mechanism of action for the same indication of ovarian cancer, and that therefore, the technology meets the newness criterion

The staged nature of wound healing also helps explain where GHK-Cu is proposed to act

2018;109:92633 Wiley

By recruiting host mitochondria to its parasit ophorous vacuole, Toxoplasma gondii prevents the release of mitochondrial danger-associated molecular patterns (DAMPs) such as mtDNA, which would otherwise activate cytosolic DNA sensors like cGAS-STING (Jin et al., 2023)