10.1016/j.coi.2016.05.010 181 MorrisG
As an antioxidant, glutathione neutralizes free radicalsunstable molecules that can cause inflammation and aging
10.1074/jbc.M504604200 J
However, AARS is an exception, which relies on lactate-AMP as an intermediate to directly transfer lactyl group to the lysine residues of target proteins with the assistance of ATP [25, 26] As the most well-studied writer, p300-catalyzed lactylation mainly promotes gene transcription [28,29,30,31,32,33,34,35,36,37,38,39] and maintains normal protein structure and functions [40,41,42,43,44,45]
We chose to look predominately at homogenization of gels as a batch purification method because most laboratories have access to plastic eppendorf homogenizers or similar
Lactate as a metabolite and a regulator in the central nervous system