doi: 10.1016/j.ejphar.2015.12.019 130 ChenJWangWJiangMYangMWeiW
Comprising the initial 29 amino acids of the native hormone, this analog appears to stimulate GHRH receptors located in the somatotroph cells of the anterior pituitary gland, thereby facilitating the release of growth hormone
These NPs have demonstrated a potential tumor-suppressing effect by attenuating Wnt expression in vitro and in vivo (Liu T
However, translating these findings into clinical applications presents significant challenges [278]
EXP: 12/2027 - 03/2028
Antibodies used were as follows: FoxO3a (Cell Signaling Technology, #12829), phospho-FoxO3a (Ser253) (HUABIO, ST49-01), Atrogin-1 (Proteintech, 67172-1-Ig, RRID: AB_2882468), MuRF-1 (Proteintech, 55456-1-AP, RRID: AB_11182630), GAPDH (Proteintech, 60004-1-Ig, RRID: AB_2107436), and HRP-conjugated secondary antibodies (Proteintech, SA00001-1/SA00001-2)