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Cell and Tissue Research, 377(2), 153159

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Oxidative phosphorylation (OXPHOS) depends on iron ions as essential cofactors in ETC complexes, including cytochrome c oxidase, where they participate directly in electron transfer and oxygen reduction

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Under oxidizing conditions, copper ions inhibit cytosolic mitoTAD and MAD key enzymes Cdc48, while the expression of matrix protease CLpP is related to ATP7A levels [157, 158]