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The saikosaponin family exerts its antidepressant effects through various pathways: promoting ubiquitination of NLRP3 inflammasome, inhibiting NF-B pathway, upregulating the expression of anti-ferroptotic proteins (GPX4, Nrf2, and SLC7A11) and attenuating lipid peroxidation

Polmacoxib is an orally active dual inhibitor of COX-2 and carbonic anhydrase (CA)

When used together, these peptides may offer complementary benefits for tissue repair and recovery

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Together they present a multi-pathway approach to regeneration, making the blend a focus of ongoing experimental and comparative recovery research