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Upon cellular fractionation, mutants exhibited a significant decrease in tGSH and GSH in the cytosolic fraction compared to controls, where most cellular GSH is located (Extended Data Fig

insulin is one of the most well-known examples, and modern metabolic medications like GLP-1 receptor agonists have transformed how we treat diabetes and obesity

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Standard allometric scaling would suggest a far lower human-equivalent dose

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For a neighboring investigational contrast, our cagrilintide vs retatrutide comparison applies the same evidence-tier discipline