Key Industry Developments In August 2025 , research from Rockefeller University identified mitochondrial glutathione as a critical metabolite enabling breast cancer metastasis, with elevated levels in metastatic cells facilitating survival in new tissues through signaling mechanisms rather than antioxidant activity
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By conceptualizing uric acid biology as a dynamic, multi-state process, this review offers an integrated perspective on hyperuricemia-associated diseases and suggests directions for future targeted therapeutic research
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45, 46 The labile ironsulfur (Fe-S) cluster present in the active site of aconitase is a major target of excessive mitochondrial superoxide
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