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A greater than 40% increase in Memo expression has been linked to adverse clinical parameters in primary breast cancer and serves as an independent prognostic marker for early distant metastasis [121]

Interestingly, an in vitro study involving rat Leydig cell line R2C reported decreased progesterone (the precursor of testosterone) release along with a decrease in the expression level of StAR, CYP11A1 and 3-HSD proteins upon incubation with Pb (50, 100, 200, 400 M) for 24 h [203]

Glutathione oxidized (L-Glutathione oxidized), an oxidized form of the antioxidant L-glutathione, acts as a signaling molecule that trigger the activation of antioxidant genes

[DOI] [PMC free article] [PubMed] [Google Scholar] Greiss F

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