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Improper Injection Site Not All Injection Sites Are Equal Choosing the wrong injection site can lead to discomfort, complications, or even ineffective absorption of Vitamin B12

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The Ehlers-Danlos Societys guidance on orthopedic management notes that an irritant injection to stabilize the sacroiliac joint (a frequent pain source in hEDS) can help in cases of isolated SI joint instability, though it remains somewhat controversial