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Among other symptoms, pellagra is characterized by dementia

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C-reactive protein (CRP), an active regulator of host innate immunity, is a biomarker of severe COVID-19 disease, including lung and atherosclerotic disease progression

Under the influence of external environmental factors, cells use lysosomes to degrade their own damaged, degenerated, or senescent macromolecules as well as organelles (such as mitochondria, and endoplasmic reticulum)

225 , 226 An additional explanation under investigation is that hearing loss is an early manifestation of the underlying brain changes that cause the various forms of dementia

Pantazatos SP, et al